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Introduction Transforming care Investing in our people Accelerating possibilities Protecting the environment Creating value responsibly Appendix Protecting the environment Environmental impact1 Unit 2018 2019 2020 2021 2022 Total municipal water consumed Million cubic meters 0.568 0.581 0.618 0.664 0.731 Total fresh water consumed Million cubic meters 0.121 0.109 0.119 0.185 0.130 Total process water discharged Million cubic meters 0.057 0.068 0.109 0.112 0.208 Total domestic water discharged Million cubic meters 0.412 0.430 0.511 0.590 0.519 Cubic meters water Water intensity consumed/USD millions 70 64 74 71 68 net sales Total non-hazardous and hazardous waste generated Metric tons 12,372 12,196 10,936 12,796 13,051 Total non-hazardous waste generated Metric tons 11,579 11,200 9,978 11,703 11,977 Total non-hazardous waste recycled Metric tons 9,667 8,943 7,843 8,673 8,563 Total non-hazardous waste energy recovered Metric tons 1,332 1,744 1,545 1,962 2,124 Total non-hazardous waste disposed to landfill Metric tons 581 514 591 1,067 1,290 Total hazardous waste generated Metric tons 792 996 958 1,093 1,074 Total hazardous waste recovered Metric tons 76 57 94 103 100 Total hazardous waste energy recovered Metric tons 310 362 376 468 449 Total hazardous waste treatment Metric tons 247 240 292 307 270 Total hazardous waste incinerated Metric tons 135 218 152 181 225 Total hazardous waste landfilled Metric tons 0 0 14 1 1 Total hazardous waste recycled Metric tons 24 119 29 33 29 Environmental notice of violation # 0 3 0 0 0 1 Environmental impact metrics coverage includes scopes 1 and 2 inclusive of all manufacturing and key distribution sites only, which represent approximately 67% of total employees. 64 2022 Performance Report

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