Introduction Transforming care Investing in our people Accelerating possibilities Protecting the environment Creating value responsibly Appendix Keeping our supply chain Boston Scientific utilizes internal and external sterilization facilities as part of building a resilient global supply chain. resilient and reliable Similar to other medical device manufacturers, we require sterilization, like ethylene oxide (EtO), so we can continue to To ensure we are able to deliver for the more than 33 million provide innovative and life-enhancing medical solutions. All patients annually who rely on our life-changing technology, our facilities comply with current permit requirements as well as our end-to-end global supply chain organization is supported regulatory guidelines, and we have a variety of technologies in by an agile network adept at continuously responding to place to measure and control emissions. We support continuous changing market conditions globally through supplier, improvements to reduce the use of EtO and efforts to innovate Our operations in Penang, Malaysia serve manufacturing and distribution strategies. Our global supply sterilization for medical devices and were the first company to as a distribution warehouse and operational base for planning, logistics, customer care and chain network spans 15 principal manufacturing facilities, join the U.S. FDA EtO Sterilization Master File Pilot Program. equipment service repair. as well as various distribution, customer fulfillment and Going forward, we will continue to work with the U.S. FDA technology centers around the world. and other agencies to explore new methods. In the past year, we expanded our regionalized distribution approach within our global supply chain network. The expansion included our first Asian regional distribution center in Penang, Malaysia, now our hub for Asia Pacific (APAC) markets. We built the facility next to a manufacturing site we opened in 2017, giving us added capacity to support global growth as well as access to local talent. Our proximity to regional customers saves time and “ We are proud to be part of limits carbon emissions. Each year, our Malaysia team will deliver Delivering for patients and providers in 2022 the company’s first global products representing our interventional cardiology, endoscopy, distribution hub in Asia. Our peripheral interventions and urology divisions to customers ~37 million around the world. team in Penang is committed products delivered to serving people in the For more on our climate-related initiatives, region and delivering products see Protecting the environment. 21,000+ needed by customers and Global Supply Chain team members their patients.” 10,000+ Jason Khoo active direct and indirect suppliers vice president, Global Supply Chain APAC 52 2022 Performance Report