Introduction Transforming care Investing in our people Accelerating possibilities Protecting the environment Creating value responsibly Appendix Global Reporting Initiative (GRI) index The GRI Standards represent global best practices for reporting publicly on a range of ESG impacts. We continue to expand the scope of our ESG metrics and disclosures to topics material to our business and stakeholders. This report has been prepared with reference to the GRI Standards, using GRI 1: Foundation 2021. Applicable GRI sector standards are not currently available. The information cited in this GRI content index is for the period from January 1, 2022 to December 31, 2022. The following table includes references to our 2022 Performance Report, 2022 Annual Report on Form 10-K and other documents available on Bostonscientific.com. Indicator Description Response GRI 2: General disclosures Boston Scientific Corporation, publicly traded on New York Stock Exchange as BSX 2-1 Organizational details Global headquarters: 300 Boston Scientific Way, Marlborough, MA 01752-1234 Form 10-K, Item 2. Properties, Page 32 Locations 2-2 Entities included in the organization’s sustainability reporting Form 10-K, Exhibit 21 Where noted, scope is inclusive of all manufacturing and key distribution sites only We report and plan to update this index annually. Data in the 2022 Performance Report covers the period between 2-3 Reporting period, frequency and contact point January 1, 2022 and December 31, 2022, unless otherwise indicated Contact: Investor Relations 2-4 Restatements of information If corrections are made to previously reported data, restatements are noted within the Performance Report and Performance Report Appendix 2-5 External assurance Our energy and greenhouse gas (GHG) emissions data has been independently verified Form 10-K, Item 1. Business, Page 3 Form 10-K, Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations, 2-6 Activities, value chain, and other business relationships Page 36 Performance Report, Boston Scientific: 2022 at glance, Page 7 Performance Report, Creating value responsibly, Page 47 2-7 Employees Form 10-K, Item 1. Human Capital, Page 11 Performance Report Appendix 68 2022 Performance Report