Introduction Transforming care Investing in our people Accelerating possibilities Protecting the environment Creating value responsibly Appendix Metrics summary Our metrics summary provides key performance data organized under five pillars that align to leading environmental, social and governance (ESG) ratings and inclusion within sustainability indices. Transforming care Product quality and safety Unit 2018 2019 2020 2021 2022 Class I recalls # 0 0 3 3 0 Class II recalls # 5 7 15 8 12 Regulatory inspections # 76 87 85 97 81 Form 483 observations # 7 0 0 5 1 FDA warning letters Yes/No No No No No No Innovation Unit 2018 2019 2020 2021 2022 1 Research & Development (R&D) spend USD millions 1,113 1,174 1,143 1,204 1,323 2 R&D spend as a percent of net sales % 11.3 10.9 11.5 10.1 10.4 Number of R&D positions FTE 1,453 2,040 2,114 2,136 2,469 1 Represents GAAP R&D expense per corresponding Annual Report on Form 10-K. 2 Represents GAAP R&D expense as a percent of GAAP net sales per corresponding Annual Report on Form 10-K. 59 2022 Performance Report