Appendix A - Net Sales Detail - Cardiovascular Three Months Ended December 31, 2022 and 2021 Year-over-Year Change Q4 Q4 Less: Impact of (in millions) 2022 2021 As Reported Basis Foreign Currency Operational Basis CARDIOVASCULAR SEGMENT: ICTx UNITED STATES $ 176 $ 185 (5.3) % — % (5.3) % INTERNATIONAL 386 390 (1.1) % (11.3) % 10.2 % WORLDWIDE $ 561 $ 575 (2.4) % (7.6) % 5.2 % Watchman UNITED STATES $ 253 $ 205 23.6 % — % 23.6 % INTERNATIONAL 27 28 (2.9) % (12.1) % 9.2 % WORLDWIDE $ 280 $ 233 20.5 % (1.4) % 21.9 % Cardiac Rhythm Management UNITED STATES $ 332 $ 312 6.4 % — % 6.4 % INTERNATIONAL 189 202 (6.6) % (11.5) % 4.9 % WORLDWIDE $ 521 $ 514 1.3 % (4.5) % 5.8 % Electrophysiology UNITED STATES $ 79 $ 32 143.4 % — % 143.4 % INTERNATIONAL 88 68 30.1 % (14.5) % 44.5 % WORLDWIDE $ 167 $ 100 66.7 % (9.8) % 76.4 % CARDIOLOGY UNITED STATES $ 840 $ 735 14.3 % — % 14.3 % INTERNATIONAL 690 687 0.3 % (11.7) % 12.0 % WORLDWIDE $ 1,529 $ 1,422 7.5 % (5.6) % 13.2 % PERIPHERAL INTERVENTIONS UNITED STATES $ 266 $ 248 7.5 % — % 7.5 % INTERNATIONAL 210 214 (2.1) % (12.4) % 10.3 % WORLDWIDE $ 476 $ 462 3.0 % (5.8) % 8.8 % 16 Q4 2022 Financial & Operational Highlights | February 1, 2023