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Appendix C - Additional Non-GAAP Reconciliations 12 Months Ended China net sales growth 2022 vs 2021 12/31/2022 Net sales growth, as reported 17 % Less: Impact of foreign currency fluctuations (5) % Net sales growth, operational 22 % Three Months Ended 12 Months Ended Latin America net sales growth 2022 vs 2021 12/31/2022 12/31/2022 Net sales growth, as reported 16 % 27 % Less: Impact of foreign currency fluctuations — % (1) % Net sales growth, operational 16 % 28 % 12 Months Ended Coronary therapies net sales growth 2022 vs 2021 12/31/2022 Net sales growth, as reported — % Less: Impact of foreign currency fluctuations (7) % Net sales growth, operational 7 % Three Months Ended Electrophysiology International net sales growth 2022 vs 2021 12/31/2022 Net sales growth, as reported 30 % Less: Impact of foreign currency fluctuations (15) % Net sales growth, operational 45 % Less: Impact of recent acquisitions/divestitures 5 % Net sales growth, organic 40 % 26 Q4 2022 Financial & Operational Highlights | February 1, 2023

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