Appendix A - Net Sales Detail - Cardiovascular Year Ended December 31, 2022 and 2021 Year-over-Year Change Less: Impact of As Reported Foreign Operational (in millions) YTD 2022 YTD 2021 Basis Currency Basis CARDIOVASCULAR SEGMENT: ICTx UNITED STATES $ 744 $ 778 (4.4) % — % (4.4) % INTERNATIONAL 1,485 1,431 3.8 % (10.3) % 14.0 % WORLDWIDE $ 2,228 $ 2,209 0.9 % (6.6) % 7.5 % Watchman UNITED STATES $ 915 $ 729 25.5 % — % 25.5 % INTERNATIONAL 103 100 3.7 % (9.5) % 13.2 % WORLDWIDE $ 1,019 $ 829 22.9 % (1.1) % 24.0 % Cardiac Rhythm Management UNITED STATES $ 1,337 $ 1,214 10.1 % — % 10.1 % INTERNATIONAL 763 805 (5.1) % (10.7) % 5.5 % WORLDWIDE $ 2,100 $ 2,019 4.0 % (4.3) % 8.3 % Electrophysiology UNITED STATES $ 275 $ 128 114.6 % — % 114.6 % INTERNATIONAL 310 237 30.8 % (13.5) % 44.2 % WORLDWIDE $ 585 $ 365 60.2 % (8.8) % 68.9 % CARDIOLOGY UNITED STATES $ 3,271 $ 2,850 14.8 % — % 14.8 % INTERNATIONAL 2,662 2,572 3.5 % (10.7) % 14.1 % WORLDWIDE $ 5,932 $ 5,422 9.4 % (5.1) % 14.5 % PERIPHERAL INTERVENTIONS UNITED STATES $ 1,048 $ 996 5.2 % — % 5.2 % INTERNATIONAL 850 824 3.3 % (10.5) % 13.8 % WORLDWIDE $ 1,899 $ 1,820 4.4 % (4.8) % 9.1 % 18 Q4 2022 Financial & Operational Highlights | February 1, 2023