FY 2022 vs. FY 2021 Restated Net Sales New Segment Presentation Less: Impact Less: Impact of Foreign of Recent FY FY As Reported Currency Operational Acquisitions / Organic (in millions) 2022 2021 Basis Fluctuations Basis Divestitures Basis ENDOSCOPY $ 2,221 $ 2,141 3.7 % (4.4) % 8.1 % — % 8.1 % UROLOGY 1,773 1,583 12.0 % (2.9) % 14.9 % 5.3 % 9.7 % NEUROMODULATION 917 909 0.9 % (2.6) % 3.5 % — % 3.5 % MEDSURG 4,911 4,633 6.0 % (3.5) % 9.5 % 1.8 % 7.7 % ICTx 2,228 2,209 0.9 % (6.6) % 7.5 % — % 7.5 % WATCHMAN 1,019 829 22.9 % (1.1) % 24.0 % — % 24.0 % CARDIAC RHYTHM MANAGEMENT 2,100 2,019 4.0 % (4.3) % 8.3 % 1.6 % 6.7 % ELECTROPHYSIOLOGY 585 365 60.2 % (8.7) % 68.9 % 51.1 % 17.8 % CARDIOLOGY 5,932 5,422 9.4 % (5.1) % 14.5 % 4.0 % 10.4 % PERIPHERAL INTERVENTIONS 1,899 1,820 4.4 % (4.8) % 9.1 % — % 9.1 % CARDIOVASCULAR 7,831 7,242 8.1 % (5.0) % 13.1 % 3.0 % 10.1 % 12,742 11,875 7.3 % (4.4) % 11.7 % 2.5 % 9.2 % † OTHER (60) 13 (+100)% — % (+100)% — % (+100)% WORLDWIDE NET SALES $ 12,682 $ 11,888 6.7 % (4.4) % 11.1 % 2.4 % 8.7 % 29 Q4 2022 Financial & Operational Highlights | February 1, 2023