Introduction Transforming care Investing in our people Accelerating possibilities Protecting the environment Creating value responsibly Appendix 2022 highlights Transforming Investing in Accelerating Protecting the Creating value care our people possibilities environment responsibly 80% $67 million 33+ million overall employee patients served engagement score donated to fund medical 76% ~37 million research, fellowships, renewable electricity2 42.6% education and charitable products delivered in 2022 $1.3+ billion organizations globally 1 supervisor and manager SBTi approval invested in R&D roles held by women (global) 99%+ 121,000+ net-zero and greenhouse gas of all employees have Zero findings women and people of color emission reduction targets completed Code of 22.6% identified in health action plans approved by the Science Based Conduct training resulting in action following supervisor and manager to advance equitable care in Targets initiative (SBTi) 325+ external audit days roles held by multicultural underserved U.S. communities employees (U.S./Puerto Rico) 1 Represents GAAP R&D expense per 2022 Annual Report on Form 10-K. 2 Purchased electricity matched with electricity from renewable sources, inclusive of all manufacturing and key distribution sites only. 10 2022 Performance Report