Introduction Transforming care Investing in our people Accelerating possibilities Protecting the environment Creating value responsibly Appendix Research and development (R&D) R&D Centers of Excellence: Building capability for new product development to advance innovation We design medical solutions by applying scientific rigor to our Marlborough, U.S. Clonmel, Ireland Shanghai, China most promising ideas. Our product development approach • Biological innovation • Metal additive • Electronic medical equipment addresses health care problems while adhering to stringent • Computational analysis business, technical and quality standards. As we monitor • Direct visualization product life cycles, our teams consider next-generation improvements as well as technologies that can help solve unmet clinical needs. Boston Scientific has 10 R&D Centers of Excellence for new product development, which are located across the United States, the European Union, Costa Rica, India and China, and give the company’s innovators a collaborative platform to investigate treatment approaches. In each center, engineers and scientists specialize in key areas of product performance to identify best practices and enhance patient care. A cross-divisional committee of senior leaders guides their work to ensure findings are shared across our full R&D pipeline. For example, in our battery design and manufacturing Center of Excellence, we design implantable batteries for neuromodulation and cardiac rhythm management devices. We manufacture these critical components internally to ensure quality and avoid supply issues. Heredia, Costa Rica Maple Grove, U.S. Arden Hills, U.S. Gurugram, India • Computational analysis • Catheter material and design • Battery design and manufacturing • Human factors and • Nitinol product design • Computational analysis industrial design • Pharmaceutical sciences • Electronic medical equipment 14 2022 Performance Report